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Thyroid hormones and cardiac arrhythmias
- 1.0343337 - FGÚ 2011 RIV US eng J - Journal Article
Tribulová, N. - Knezl, V. - Shainberg, A. - Seki, S. - Soukup, Tomáš
Thyroid hormones and cardiac arrhythmias.
Vascular Pharmacology. Roč. 52, 3-4 (2010), s. 102-112. ISSN 1537-1891. E-ISSN 1879-3649
R&D Projects: GA ČR(CZ) GA304/08/0256
Grant - others:VEGA(SK) 2/0049/09; APVV(SK) 51-059505; APVV(SK) 51-017905
Institutional research plan: CEZ:AV0Z50110509
Keywords : thyroid hormone * arrhythmias * ion channels * connexin-43
Subject RIV: FA - Cardiovascular Diseases incl. Cardiotharic Surgery
Impact factor: 2.174, year: 2010
Chronic changes in the amount of circulating thyroid hormone due to thyroid dysfunction or systemic disease result in structural, electrophysiological and Ca2+ handling remodeling, while acute changes may affect basal activity of cardiac cells membrane systems. Consequently, long-term or rapid modulation of sarcolemmal ion channels, Ca2+ cycling proteins and intercellular communicating channels by thyroid hormone may affect heart function as well as susceptibility of the heart to arrhythmias. This aspect including pro- and anti-arrhythmic potential of thyroid hormone is highlighted in this review
Permanent Link: http://hdl.handle.net/11104/0185841
Number of the records: 1