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Melatonin interactions with blood pressure and vascular function during l-NAME-induced hypertension
- 1.0343240 - FGÚ 2011 RIV DK eng J - Journal Article
Paulis, L. - Pecháňová, Olga - Zicha, Josef - Barta, A. - Gardlik, R. - Celec, P. - Kuneš, Jaroslav - Šimko, F.
Melatonin interactions with blood pressure and vascular function during l-NAME-induced hypertension.
Journal of Pineal Research. Roč. 48, č. 2 (2010), s. 102-108. ISSN 0742-3098. E-ISSN 1600-079X
R&D Projects: GA AV ČR(CZ) IAA500110902
Grant - others:VEGA(SK) 1/0187/09; VEGA(SK) 2/0178/09; APVV(SK) 0538-07; EC(XE) 2009-237834
Institutional research plan: CEZ:AV0Z50110509
Keywords : endothelium-derived constricting factor * melatonin * nitric oxide
Subject RIV: FA - Cardiovascular Diseases incl. Cardiotharic Surgery
Impact factor: 5.855, year: 2010
To elucidate the possible role of the nitric oxide (NO) pathway in the hemodynamic actions of melatonin, the effects of this indolamine on vascular function during hypertension induced by NO-synthase (NOS) inhibition were investigated. It is evident that, in addition to the reduction of the oxidative load, the restoration of the NO pathway seems to play an important role in the antihypertensive effect of melatonin
Permanent Link: http://hdl.handle.net/11104/0185759
Number of the records: 1