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Signaling by purinergic receptors and channels in the pituitary gland

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    0343229 - FGÚ 2011 RIV IE eng J - Journal Article
    Stojilkovic, S. S. - He, M. L. - Koshimizu, T. - Balík, A. - Zemková, Hana
    Signaling by purinergic receptors and channels in the pituitary gland.
    Molecular and Cellular Endocrinology. Roč. 314, č. 2 (2010), s. 184-191. ISSN 0303-7207. E-ISSN 1872-8057
    R&D Projects: GA ČR(CZ) GA305/07/0681
    Institutional research plan: CEZ:AV0Z50110509
    Keywords : purinergic receptors * ATP * anterior pituitary
    Subject RIV: ED - Physiology
    Impact factor: 4.119, year: 2010

    In the pituitary gland, adenosine 5’-triphosphate is released from the endings of magnocellular hypothalamic neurons and by anterior pituitary cells through still not well-characterized pathway(s). This gland also expresses several members of purinergic receptors: P1, P2X and P2Y. P2X receptors stimulate electrical activity and modulate InsP3-dependent calcium release from intracellular stores, whereas P1 receptors terminate electrical activity. Calcium-mobilizing P2Y receptors are predominantly expressed in non-secretory cells of the anterior and posterior pituitary
    Permanent Link: http://hdl.handle.net/11104/0185752

     
     
Number of the records: 1  

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