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Synthesis of novel racemic carbocyclic nucleosides derived from 5,6-disubstituted norbornene
- 1.0342649 - ÚOCHB 2011 RIV CZ eng J - Journal Article
Šála, Michal - Hřebabecký, Hubert - Dračínský, Martin - Masojídková, Milena - De Palma, A. M. - Neyts, J. - Holý, Antonín
Synthesis of novel racemic carbocyclic nucleosides derived from 5,6-disubstituted norbornene.
Collection of Czechoslovak Chemical Communications. Roč. 75, č. 1 (2010), s. 1-20. ISSN 0010-0765
R&D Projects: GA MŠMT 1M0508; GA AV ČR 1QS400550501
Institutional research plan: CEZ:AV0Z40550506
Keywords : carbocyclic nucleosides * norbornenes * Coxsackie virus
Subject RIV: CC - Organic Chemistry
Impact factor: 0.853, year: 2010
This study concerns synthesis of novel racemic conformationally locked nucleosides with bicyclo[2.2.1]heptene ring system substituted with nucleobase and hydroxymethyl group at positions 5 and 6 and their derivatives (saturated a cis-hydroxylated compounds). Biological activity of the newly prepared compounds is described.
Permanent Link: http://hdl.handle.net/11104/0185329
Number of the records: 1