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Intramolecular Direct C-H Arylation Approach to Fused Purines. Synthesis of Purino[8,9-f]phenanthridines and 5,6-Dihydropurino[8,9-a]isoquinolines
- 1.0342381 - ÚOCHB 2011 RIV US eng J - Journal Article
Čerňa, Igor - Pohl, Radek - Klepetářová, Blanka - Hocek, Michal
Intramolecular Direct C-H Arylation Approach to Fused Purines. Synthesis of Purino[8,9-f]phenanthridines and 5,6-Dihydropurino[8,9-a]isoquinolines.
Journal of Organic Chemistry. Roč. 75, č. 7 (2010), s. 2302-2308. ISSN 0022-3263. E-ISSN 1520-6904
R&D Projects: GA MŠMT(CZ) LC06077
Institutional research plan: CEZ:AV0Z40550506
Keywords : purines * cross-coupling * fused heterocycles * C-H activation
Subject RIV: CC - Organic Chemistry
Impact factor: 4.002, year: 2010
Intramolecular direct C-H arylations were employed as a key step in the synthesis of hitherto unknown fused purine systems. 13-Substituted purino[8,9-f]phenanthridines were prepared from 9-(2-bromophenyl)purines and 2-bromophenylboronic acid, while 11-substituted 5,6-dihydropurino[8,9-a]isoquinolines from 9-(2-chlorophenethyl)purines.
Permanent Link: http://hdl.handle.net/11104/0185129
Number of the records: 1