Comparative effect of amidated pectin and psyllium on cholesterol homeostasis in rats

0342032 - ÚŽFG 2011 RIV PL eng J - Journal Article
Marounek, Milan - Volek, Z. - Skřivanová, E. - Tůma, J. - Dušková, D.
Comparative effect of amidated pectin and psyllium on cholesterol homeostasis in rats.
Central European Journal of Biology. Roč. 5, č. 3 (2010), s. 299-303. ISSN 1895-104X
Institutional research plan: CEZ:AV0Z50450515
Keywords : Cholesterol homeostazis * Pectin * Psyllium
Subject RIV: GH - Livestock Nutrition
Impact factor: 0.685, year: 2010

The effects of amidated pectin and psyllium were compared in rats fed diets supplemented with palm fat and cholesterol at 50 and 10 g/kg, respectively. Amidated pectin and psyllium significantly decreased serum cholesterol from 3.41 μmol/ml to 1.68 and 2.04 μmol/ml, respectively, and hepatic cholesterol from 31.9 μmol/g to 7.2 and 9.0 μmol/g, respectively. Faecal cholesterol content was significantly increased in rats that were fed amidated pectin, and non-significantly increased in rats that were fed psyllium. In conclusion, amidated pectin, a novel sequestrant of sterols, demonstrated a similar effect on rat serum and hepatic cholesterol concentration to psyllium, which is a well-established hypocholesterolaemic agent.
Permanent Link: http://hdl.handle.net/11104/0184862