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Expression profiles of proliferative and antiapoptotic genes in sporadic and colitis-related mouse colon cancer models
- 1.0341831 - FGÚ 2011 RIV US eng J - Journal Article
Švec, J. - Ergang, Peter - Mandys, V. - Kment, M. - Pácha, Jiří
Expression profiles of proliferative and antiapoptotic genes in sporadic and colitis-related mouse colon cancer models.
International Journal of Experimental Pathology. Roč. 91, č. 1 (2010), s. 44-53. ISSN 0959-9673. E-ISSN 1365-2613
R&D Projects: GA MZd(CZ) NS9982; GA MZd(CZ) 1A8651
Institutional research plan: CEZ:AV0Z50110509
Keywords : colorectal carcinoma * mouse
Subject RIV: FP - Other Medical Disciplines
Impact factor: 2.127, year: 2010
These findings suggest that the genetic background and/or the molecular mechanisms of tumorigenesis associated with genotoxic insults and colonic inflammation influence the gene expression of survivin, telomerase catalytic subunit, cyclooxygenase 2, integrin-linked kinase, and the regulatory factors c-MYB and Tcf-4 in colon epithelial neoplasia
Permanent Link: http://hdl.handle.net/11104/0184697
Number of the records: 1