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Anticonvulsant doses of ganaxolone do not compromise motor performance in immature rats

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    0341807 - FGÚ 2011 RIV IE eng J - Journal Article
    Mareš, Pavel - Stehlíková, M.
    Anticonvulsant doses of ganaxolone do not compromise motor performance in immature rats.
    Neuroscience Letters. Roč. 469, č. 3 (2010), s. 396-399. ISSN 0304-3940. E-ISSN 1872-7972
    R&D Projects: GA MŠMT(CZ) LC554; GA ČR GA203/06/1605
    Institutional research plan: CEZ:AV0Z50110509
    Keywords : ganaxolone * epileptic seizures * motor abilities
    Subject RIV: FH - Neurology
    Impact factor: 2.055, year: 2010

    Anticonvulsant activity of ganaxolone against cortical epileptic afterdischarges was demonstrated in 12-, 18- and 25-day-old rats. The effective doses (20 and 40 mg/kg) did not significantly affected motor performance of the same age groups of rats
    Permanent Link: http://hdl.handle.net/11104/0184681

     
     
Number of the records: 1  

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