Metabolic Rhythms of the Cyanobacterium Cyanothece sp ATCC 51142 Correlate with Modeled Dynamics of Circadian Clock

0341129 - ÚVGZ 2012 RIV US eng J - Journal Article
Červený, Jan - Nedbal, Ladislav
Metabolic Rhythms of the Cyanobacterium Cyanothece sp ATCC 51142 Correlate with Modeled Dynamics of Circadian Clock.
Journal of Biological Rhythms. Roč. 4, č. 24 (2009), s. 295-303. ISSN 0748-7304. E-ISSN 1552-4531
R&D Projects: GA ČR(CZ) GA206/09/1284
Institutional research plan: CEZ:AV0Z60870520
Keywords : circadian clock * cyanobacteria * model * photosynthesis * respiration
Subject RIV: CE - Biochemistry
Impact factor: 4.418, year: 2009

This paper aims to reveal the dynamic features that occur during the metabolism of the unicellular, nitrogen fixing cyanobacterium Cyanothece sp. when exposed to diverse circadian forcing.Measured quantities showed interesting dynamic patterns releated to expected circadian behavior, especially reflected by sharp peak of respiration that coincides with the putative hydrocarbon catabolism. In the long day regime (LD 16:8), these events may mark the transition from photosynthetic metabolism to nitrogen metabolism that occurs at dusk, and thus cannot be triggered by the darkness that comes later. To explore the dynamics of the link between respiration and circadian oscillations, we extrapolated model of the KaiABC oscillator from Synechococcus elongatus to Cyanothece sp. The measured peak of respiratory activity at dusk correlated strongly in its timing and time-width with the modeled peak in accumulation of the KaiB4 complex, which marks the late afternoon phase of the circadian clock.
Permanent Link: http://hdl.handle.net/11104/0184208