Compact and low-cost biosensor based on novel approach to spectroscopy of surface plasmons

0341078 - ÚFE 2010 RIV GB eng J - Journal Article
Piliarik, Marek - Vala, Milan - Tichý, Ivo - Homola, Jiří
Compact and low-cost biosensor based on novel approach to spectroscopy of surface plasmons.
Biosensors and Bioelectronics. Roč. 24, č. 12 (2009), s. 3430-3435. ISSN 0956-5663. E-ISSN 1873-4235
Institutional research plan: CEZ:AV0Z20670512
Keywords : SPR sensor * biosensor * diffraction grating
Subject RIV: JB - Sensors, Measurment, Regulation
Impact factor: 5.429, year: 2009

A compact 4-channel surface plasmon resonance (SPR) sensor based on a novel approach to spectroscopy of surface plasmons is reported. The sensor employs a special diffraction grating structure, which simultaneously couples light into a surface plasmon and disperses light for spectral readout of SPR signal. The sensor is demonstrated to measure refractive index changes as small as 3×10−7 and to detect short oligonucleotides down to 200 pM.
Permanent Link: http://hdl.handle.net/11104/0184176