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HMGB proteins: Interactions with DNA and chromatin

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    0340903 - BFÚ 2010 RIV US eng J - Journal Article
    Štros, Michal
    HMGB proteins: Interactions with DNA and chromatin.
    Biochimica et Biophysica Acta-Gene Regulatory Mechanisms. Roč. 1799, 1-2 (2010), s. 101-113. ISSN 1874-9399. E-ISSN 1876-4320
    R&D Projects: GA ČR(CZ) GA204/08/1530; GA AV ČR(CZ) IAA400040702
    Institutional research plan: CEZ:AV0Z50040507; CEZ:AV0Z50040702
    Keywords : HMG-box * DNA-protein interaction * chromatin
    Subject RIV: BO - Biophysics
    Impact factor: 4.000, year: 2010

    The paper is a review of current knowledge of HMGB proteins. HMGB proteins are members of the High Mobility Group (HMG) superfamily, possessing a unique DNA-binding domain, the HMG-box, which can bind non-B-type DNA structures (bent, kinked and unwound) with high affinity, and also distort DNA by bending/looping and unwinding.
    Permanent Link: http://hdl.handle.net/11104/0184048

     
     
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