Old Herborn University Seminar Monograph. 22. Biological Consequences of Host-Microbe Interactions

0340781 - MBÚ 2010 RIV DE eng M - Monography Chapter
Kozáková, Hana - Repa, A. - Schwarzer, Martin - Tlaskalová-Hogenová, Helena - Štěpánková, Renata - Hudcovic, Tomáš - Wiedermann, U.
The role of gut microflora in mucosal tolerance induction to birch pollen in mouse allergy model.
Old Herborn University Seminar Monograph. 22. Biological Consequences of Host-Microbe Interactions. Herborn: Old Herborn University, 2009 - (Heidt, P.; Hanson, L.; Tlaskalová, H.; Rusch, V.), s. 11-19. ISBN 3-923022-33-6
R&D Projects: GA AV ČR IAA500200710; GA AV ČR 1QS500200572; GA ČR GA303/06/0974; GA ČR GA303/08/0367
Institutional research plan: CEZ:AV0Z50200510
Keywords : germ-free * microbiota * birch pollen
Subject RIV: EC - Immunology

Using germ-free and Lactobacillus plantarum-monocolonized mice we studied the role of microbiota in the development of allergic sensitization and mucosal tolerance induction in a mouse model of type I allergy to birch pollen. In our setting, the absence of the microbiota did not influence the capacity to establish tolerance via the oral or intranasal routes nor to establish an allergic immune response at the humoral or cellular levels
Permanent Link: http://hdl.handle.net/11104/0183952