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A myeloperoxidase promoter polymorphism is independently associated with mortality in patients with impaired left ventricular function
- 1.0340135 - BFÚ 2010 RIV US eng J - Journal Article
Rudolph, V. - Rudolph, T.K. - Kubala, Lukáš - Clauberg, N. - Maas, R. - Pekarová, Michaela - Klinke, A. - Lau, D. - Szöcs, K. - Meinertz, T. - Böger, R.H. - Baldus, S.
A myeloperoxidase promoter polymorphism is independently associated with mortality in patients with impaired left ventricular function.
Free Radical Biology and Medicine. Roč. 47, č. 11 (2009), s. 1584-1590. ISSN 0891-5849. E-ISSN 1873-4596
R&D Projects: GA ČR(CZ) GA524/08/1753
Institutional research plan: CEZ:AV0Z50040507; CEZ:AV0Z50040702
Keywords : myeloperoxidase * heart failure * free radicals
Subject RIV: BO - Biophysics
Impact factor: 6.081, year: 2009
Circulating levels of myeloperoxidase (MPO), a heme enzyme released upon activation of polymorphonuclear neutrophils, predict adverse outcome in patients with impaired left ventricular (LV) function. There is no association of the MPO polymorphism with total MPO protein concentration or MPO activity in plasma.
Permanent Link: http://hdl.handle.net/11104/0183441
Number of the records: 1