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Absolute levels of transcripts for mitochondrial uncoupling proteins UCP2, UCP3, UCP4, and UCP5 show different patterns in rat and mice tissues
- 1.0339391 - FGÚ 2010 RIV US eng J - Journal Article
Alán, Lukáš - Smolková, Katarína - Kronusová, Eva - Šantorová, Jitka - Ježek, Petr
Absolute levels of transcripts for mitochondrial uncoupling proteins UCP2, UCP3, UCP4, and UCP5 show different patterns in rat and mice tissues.
Journal of Bioenergetics and Biomembranes. Roč. 41, č. 1 (2009), s. 71-78. ISSN 0145-479X. E-ISSN 1573-6881
R&D Projects: GA ČR(CZ) GA303/07/0105; GA AV ČR(CZ) IAA500110701; GA MŠMT(CZ) 1P05ME794
Institutional research plan: CEZ:AV0Z50110509
Keywords : uncoupling proteins * mRNA
Subject RIV: CE - Biochemistry
Impact factor: 4.015, year: 2009
Existing controversies led us to analyze absolute mRNA levels of mitochondrial uncoupling proteins (UCP1-UCP5). Individual UCP isoform mRNA levels varied by up to four orders of magnitude in rat and mouse tissues. Also significant differences in pattern were found for rat vs. mouse tissues. We predict high antioxidant/antiapoptotic UCP function in tissues with higher UCP mRNA content
Permanent Link: http://hdl.handle.net/11104/0182936
Number of the records: 1