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Mechanisms participating in oxidative damage of isolated rat hepatocytes
- 1.0338637 - FGÚ 2010 RIV DE eng J - Journal Article
Červinková, Z. - Křiváková, P. - Lábajová, A. - Roušar, T. - Lotková, H. - Kučera, O. - Endlicher, R. - Červinka, M. - Drahota, Zdeněk
Mechanisms participating in oxidative damage of isolated rat hepatocytes.
Archives of Toxicology. Roč. 83, č. 4 (2009), s. 363-372. ISSN 0340-5761. E-ISSN 1432-0738
R&D Projects: GA ČR(CZ) GA303/06/1261
Institutional research plan: CEZ:AV0Z50110509
Keywords : hepatocytes * oxidative damage * mitochondrial enzymes
Subject RIV: CE - Biochemistry
Impact factor: 3.312, year: 2009
It was evaluated concentration dependence and time course of the oxidative damage of cytoplasmic membrane and mitochondrial structure and function. It was found that most sensitive indicators of peroxidative damage are changes of mitochondrial membrane potential and oxidation of NADH-dependent substrates
Permanent Link: http://hdl.handle.net/11104/0182361
Number of the records: 1