New peptides with antimicrobial activity isolated from the venom of the bumblebee Bombus pascuorum (Hymenoptera: Apidae)

0338112 - ÚOCHB 2011 CZ eng C - Conference Paper (international conference)
Ježek, Rudolf - Janechová, D. - Cvačka, Josef - Slaninová, Jiřina - Voburka, Zdeněk - Hovorka, Oldřich - Fučík, Vladimír - Borovičková, Lenka - Maloň, Petr - Čeřovský, Václav
New peptides with antimicrobial activity isolated from the venom of the bumblebee Bombus pascuorum (Hymenoptera: Apidae).
Biologically Active Peptides. 11th Conference. Praha: Institut of organic Chemistry and Biochemistry ASCR, 2009 - (Slaninová, J.), s. 51-54. Collection Symposium Series, 11. ISBN 978-80-86241-31-9.
[Biologically Active Peptides. Conference /11./. Praha (CZ), 22.04.2009-24.04.2009]
R&D Projects: GA ČR(CZ) GA203/08/0536
Institutional research plan: CEZ:AV0Z40550506
Keywords : antimicrobial peptides * alpha-helical structure * amphipathic molecule * Bombus pascuorum
Subject RIV: CC - Organic Chemistry

Six new heptadecapeptides were isolated and synthesized by standard Fmoc solid phase peptide synthesistogether with several structural analogues. Antimicrobial activities were correlated with the peptides hydrophobicity, hydrophobic moment, alpha-helicity and HPLC retention time.
Permanent Link: http://hdl.handle.net/11104/0181970