Identification and functionality of proteomes secreted by rat cardiac stem cells and neonatal cardiomyocytes

0337734 - ÚIACH 2010 RIV DE eng J - Journal Article
Šťastná, Miroslava - Chimenti, I. - Marban, E. - Van Eyk, J.E.
Identification and functionality of proteomes secreted by rat cardiac stem cells and neonatal cardiomyocytes.
Proteomics. Roč. 10, č. 2 (2010), s. 245-253. ISSN 1615-9853. E-ISSN 1615-9861
Institutional research plan: CEZ:AV0Z40310501
Keywords : animal proteomics * cardiac stem cells * neonatal cardiomyocytes
Subject RIV: CB - Analytical Chemistry, Separation
Impact factor: 4.815, year: 2010

83 unique proteins were identified after analysis by RPLC and MS. In total, 49 and 23% were NRVM-specific and CSC-specific proteins, respectively. Three proteins were found to affect rat CSC proliferation. These findings suggest that relative concentration of each protein may be crucial for cellular intertalk and for the final outcome of cardiac cell therapy.
Permanent Link: http://hdl.handle.net/11104/0181662