Polyaluminium chloride (PAX-18) - acute toxicity and toxicity for early development stages of common carp (Cyprinus carpio)

0337412 - ÚBO 2010 RIV SE eng J - Journal Article
Mácová, S. - Máchová, J. - Prokeš, Miroslav - Plhalová, L. - Široká, Z. - Dlesková, K. - Doleželová, P. - Svobodová, Z.
Polyaluminium chloride (PAX-18) - acute toxicity and toxicity for early development stages of common carp (Cyprinus carpio).
Neuroendocrinology Letters. Roč. 30, Suppl. 1 (2009), s. 192-198. ISSN 0172-780X. E-ISSN 2354-4716.
[Interdisciplinary Czech-Slovak Toxicological Conference /14./. Brno, 01.06.2009-03.06.2009]
R&D Projects: GA MZe QH71305
Institutional research plan: CEZ:AV0Z60930519
Keywords : fish * acute toxicity test * embryo-larval toxicity test * pH
Subject RIV: GL - Fishing
Impact factor: 1.047, year: 2009
http://node.nel.edu/?node_id=9497

The aim of this study is to assess the toxicity of PAX-18 in different developmental stages of common carp (Cyprinus carpio). The toxicity tests were performed according to OECD (203, 210) methodology. Acute toxicity values expressed as 96hLC50 were 753.1 ± 24.3 mg.l-1 (67.8 mg.l-1 Al). Effect on early development stage expressed as the no observed effect concentration was 10 mg.l-1 (0.9 mg.l-1 Al) the lowest observed effect concentration was 50 mg.l-1 (4.5 mg.l-1 Al). No significant effects of the preparation PAX-18 in concentrations of 50 mg.l-1 PAX-18 and in lower tested concentrations were found on length and weight parameters, morphology and histopathology. The lethal concentration of PAX-18 found in acute toxicity tests on common carp was 7-14 times higher than the concentration which is usually applied to water (5–10 mg.l-1 Al).
Permanent Link: http://hdl.handle.net/11104/0181414