Subcellular homeostasis of phytohormone auxin is mediated by the ER-localized PIN5 transporter

0335970 - ÚEB 2010 RIV GB eng J - Journal Article
Mravec, J. - Skůpa, Petr - Bailly, A. - Hoyerová, Klára - Křeček, Pavel - Bielach, A. - Petrášek, Jan - Zhang, J. - Gaykova, V. - Stierhof, Y. D. - Dobrev, Petre - Schwarzerová, K. - Rolčík, Jakub - Seifertová, Daniela - Luschnig, Ch. - Benková, E. - Zažímalová, Eva - Geisler, M. - Friml, J.
Subcellular homeostasis of phytohormone auxin is mediated by the ER-localized PIN5 transporter.
Nature. Roč. 459, č. 7250 (2009), s. 1136-1140. ISSN 0028-0836. E-ISSN 1476-4687
R&D Projects: GA AV ČR(CZ) IAA601630703; GA AV ČR KJB600380604; GA MŠMT(CZ) LC06034
Institutional research plan: CEZ:AV0Z50380511
Keywords : AtPIN5 * auxin efflux carrier * endoplasmic reticulum
Subject RIV: EB - Genetics ; Molecular Biology
Impact factor: 34.480, year: 2009

Auxin is signalling molecule which mediates spatial and temporal coordination of plant growth and development via formation of ‘auxin gradients’. These gradients result from metabolic processes and the active directional transmembrane transport of auxin, which is catalyzed by auxin efflux carriers belonging to the PIN protein family. Investigation of atypical member of the family - AtPIN5 revealed its localization on the membranes of endoplasmic reticulum. The overexpression of the protein results in the striking change in the profile of auxin metabolites. These data show the so far unknown mechanism governing the availability of the key growth regulator in plant cells.
Permanent Link: http://hdl.handle.net/11104/0180310