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A novel ATP-binding cassette transporter is responsible for resistance to viologen herbicides in the cyanobacterium Synechocystis sp. PCC 6803
- 1.0334652 - MBÚ 2010 RIV GB eng J - Journal Article
Prosecká, J. - Orlov, V. N. - Fantin, Y. S. - Zinchenko, V. V. - Babykin, M. M. - Tichý, Martin
A novel ATP-binding cassette transporter is responsible for resistance to viologen herbicides in the cyanobacterium Synechocystis sp. PCC 6803.
FEBS Journal. Roč. 276, č. 15 (2009), s. 4001-4011. ISSN 1742-464X. E-ISSN 1742-4658
R&D Projects: GA MŠMT ME 881
Institutional research plan: CEZ:AV0Z50200510
Keywords : ABC-type transporter * cyanobacteria * oxidative stress
Subject RIV: EE - Microbiology, Virology
Impact factor: 3.042, year: 2009
Viologens generate reactive oxygen species in photosynthetic cells. Three independent methyl viologen-resistant spontaneous mutants of Synechocystis sp. PCC 6803 were identified, in which the conserved residue of the Slr1174 was mutated.. The Slr1174 protein of the DUF990 family is related to the permease subunit of an ABC-2-type transporter . Our data suggest that Slr1901, Slr1174 and Slr0610 form a heteromeric ATP-binding cassette-type viologen exporter, in which each component is critical for viologen extrusion
Permanent Link: http://hdl.handle.net/11104/0179332
Number of the records: 1