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C-Nucleosides: Synthetic Strategies and Biological Applications

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    0333503 - ÚOCHB 2010 RIV US eng J - Journal Article
    Štambaský, J. - Hocek, Michal - Kočovský, P.
    C-Nucleosides: Synthetic Strategies and Biological Applications.
    Chemical Reviews. Roč. 109, č. 12 (2009), s. 6729-6764. ISSN 0009-2665. E-ISSN 1520-6890
    R&D Projects: GA MŠMT LC512; GA AV ČR IAA400550902
    Grant - others:NIH(US) 1R03TW007372-01
    Institutional research plan: CEZ:AV0Z40550506
    Keywords : nucleosides * nucleobases * biological activity * extension of genetic alphabet
    Subject RIV: CC - Organic Chemistry
    Impact factor: 35.957, year: 2009

    This comprehensive review summarizes diverse synthetic approaches to title C-nucleosides, their biological activity (cytostatic, antiviral) and the use in chemical biology (extension of genetic alphabet, studying polymerases etc.). Also an outlook of possible future development of the field is outlined.
    Permanent Link: http://hdl.handle.net/11104/0178467

     
     
Number of the records: 1  

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