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The incorporation of the novel histone variant H2AL2 confers unusual structural and functional properties of the nucleosome

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    0333079 - FGÚ 2010 RIV GB eng J - Journal Article
    Syed, S.H. - Boulard, M. - Shukla, M.S. - Gautier, T. - Travers, A. - Bednár, Jan - Faivre-Moskalenko, C. - Dimitrov, S. - Angelov, D.
    The incorporation of the novel histone variant H2AL2 confers unusual structural and functional properties of the nucleosome.
    [Inkorporace nového typu variantního histonu H2AL2 má za následek neobvyklé strukturální a funkční vlastnosti nukleozomu.]
    Nucleic Acids Research. Roč. 37, č. 14 (2009), s. 4684-4695. ISSN 0305-1048. E-ISSN 1362-4962
    Grant - others:GA MŠk(CZ) LC535; GA ČR(CZ) GA304/05/2168
    Program: LC
    Institutional research plan: CEZ:AV0Z50110509
    Keywords : nucleosome * histone * variant
    Subject RIV: EB - Genetics ; Molecular Biology
    Impact factor: 7.479, year: 2009

    Biomolecular and structural (cryo-electron microscopy) studies show that nucleosomes with incorporated variant histones H2AL2 adopts more opened structure, associates only about 130 bp of DNA and cannot be remodeled by RSC

    Biomolekulární a strukturální (kryo-elektronová mikroskopie) studie prokázaly, že nukleozom obsahující variantní histon H2AL2 má více otevřenou strukturu, asociuje pouze ca 130 pb DNA a není remodelovatelný faktorem RSC
    Permanent Link: http://hdl.handle.net/11104/0178155

     
     
Number of the records: 1  

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