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Cytostatic tetrazole–butenolide conjugates: linking tetrazole and butenolide rings via Stille coupling and biological activity of the target substances
- 1.0332654 - ÚOCHB 2010 RIV CZ eng J - Journal Article
Balšánek, V. - Tichotová, L. - Kuneš, J. - Špulák, M. - Pour, M. - Votruba, Ivan - Buchta, V.
Cytostatic tetrazole–butenolide conjugates: linking tetrazole and butenolide rings via Stille coupling and biological activity of the target substances.
Collection of Czechoslovak Chemical Communications. Roč. 74, 7/8 (2009), s. 1161-1178. ISSN 0010-0765
R&D Projects: GA MŠMT 1M0508
Grant - others:GA ČR(CZ) GA203/07/1302
Institutional research plan: CEZ:AV0Z40550506
Keywords : Pd catalysis * Cross-coupling reactions * heterocycles * tetrazoles
Subject RIV: CC - Organic Chemistry
Impact factor: 0.856, year: 2009
A series of tetrazoles linked to the butenolide core via benzene rings were prepared by the Stille coupling reaction of alpha-(tributylstannyl)butenolides and 5-(alkylsulfanyl)-1-(4-iodophenyl)tetrazoles, and the compounds were tested for antifungal and cytostatic activity.
Permanent Link: http://hdl.handle.net/11104/0177849
Number of the records: 1