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The Fischer 344 rat as a model of presbycusis
- 1.0332199 - ÚEM 2011 RIV NL eng J - Journal Article
Syka, Josef
The Fischer 344 rat as a model of presbycusis.
Hearing Research. Roč. 264, 1-2 (2010), s. 70-78. ISSN 0378-5955. E-ISSN 1878-5891
R&D Projects: GA ČR GA309/07/1336; GA MŠMT(CZ) LC554
Institutional research plan: CEZ:AV0Z50390703
Keywords : Rat * Fischer 344 * Presbycusis
Subject RIV: FH - Neurology
Impact factor: 2.428, year: 2010
http://arl-repository.lib.cas.cz/uloziste_av/UEM-P/cav_un_epca-0332199_01.pdf
Pronounced hearing loss at the end of the second year, the rapid deterioration of distortion product otoacoustic emissions with the majority of outer hair cells being present and morphologically intact, produced apparently by the disruption of prestin, and deterioration of acoustical signal processing within central auditory system supports the idea that the Fischer 344 rat strain may serve as a suitable model for studying the mechanisms of presbycusis, its prevention and treatment.
Permanent Link: http://hdl.handle.net/11104/0177523
Number of the records: 1