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Thermoresponsive hydrolytically degradable polymer micelles intended for radionuclide delivery
- 1.0331564 - ÚMCH 2010 RIV DE eng J - Journal Article
Hrubý, Martin - Koňák, Čestmír - Filippov, Sergey K. - Kučka, Jan - Větvička, David - Macková, Hana - Karlsson, G. - Edwards, K. - Říhová, Blanka - Ulbrich, Karel
Thermoresponsive hydrolytically degradable polymer micelles intended for radionuclide delivery.
Macromolecular Bioscience. Roč. 9, č. 10 (2009), s. 1016-1027. ISSN 1616-5187. E-ISSN 1616-5195
R&D Projects: GA AV ČR KAN200200651; GA ČR GA202/09/2078; GA ČR GD310/08/H077; GA MŠMT 1M0505
Institutional research plan: CEZ:AV0Z40500505; CEZ:AV0Z50200510; CEZ:AV0Z10480505
Keywords : block-copolymer micelles * drug-delivery * systems
Subject RIV: CD - Macromolecular Chemistry
Impact factor: 3.108, year: 2009
Novel polymer micelles, prepared by self-assembling thermoresponsive poly(N-isopropylacrylamide)-graft-poly[N-(2-hydroxypropyl)methacrylamide] copolymers with hydrolytically degradable N-glycosylamine groups between the polymer blocks were synthesized, characterized and proposed for delivery of diagnostic and therapeutic radionuclides into solid tumors.
Permanent Link: http://hdl.handle.net/11104/0005520
Number of the records: 1