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Genetic variability of HVRII mtDNA in cord blood and respiratory morbidity in children

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    0330444 - ÚEM 2010 RIV NL eng J - Journal Article
    Schmuczerová, Jana - Brdička, R. - Dostál, Miroslav - Šrám, Radim - Topinka, Jan
    Genetic variability of HVRII mtDNA in cord blood and respiratory morbidity in children.
    [Genetická variabilita v HVII oblasti mtDNA pupečníkové krve a respirační nemocnost u dětí.]
    Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis. Roč. 666, 1-2 (2009), s. 1-7. ISSN 0027-5107
    R&D Projects: GA MŽP SL/5/160/05
    Institutional research plan: CEZ:AV0Z50390512
    Keywords : mitochondrial DNA * genetic polymorphisms * children morbidity
    Subject RIV: DN - Health Impact of the Environment Quality
    Impact factor: 3.556, year: 2009

    It was found that the T195C transversion in HVRII is connected with an increased risk of early childhood bronchitis and with increased risk of otitis media in children aged 2–6 years. Another polymorphism, 309.nC, is associated with an increased risk of bronchitis in children aged 2–6 years.

    Bylo zjištěno, že T195C transverze v HVRII oblasti mtDNA je spojena se zvýšeným rizikem bronchitid v ranném dětství a se zvýšeným rizikem zánětu středního ucha u u dětí ve věku 2-6 let. Jiný polymorfismus, 309.nC, je spojen se zvýšeným rizikem bronchitid ve věku 2-6 let.
    Permanent Link: http://hdl.handle.net/11104/0176232

     
     
Number of the records: 1  

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