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Synthesis of (purin-6-yl)acetates and their transformations to 6-(2-hydroxyethyl)- and 6-(carbamoylmethyl)purines
- 1.0330122 - ÚOCHB 2010 RIV CZ eng J - Journal Article
Hasník, Zbyněk - Pohl, Radek - Klepetářová, Blanka - Hocek, Michal
Synthesis of (purin-6-yl)acetates and their transformations to 6-(2-hydroxyethyl)- and 6-(carbamoylmethyl)purines.
Collection of Czechoslovak Chemical Communications. Roč. 74, 7/8 (2009), s. 1035-1059. ISSN 0010-0765
R&D Projects: GA MŠMT 1M0508; GA AV ČR 1QS400550501
Institutional research plan: CEZ:AV0Z40550506
Keywords : purines * nucleosides * cross-coupling * organozinc reagents
Subject RIV: CC - Organic Chemistry
Impact factor: 0.856, year: 2009
Cross-coupling reactions of 6-halopurines with Reformatsky reagent gave (purin-6-yl)acetates which were further transformed to 6-(2-hydroxyethyl)- and 6-(carbamoylmethyl)purines by reduction or amidation.
Permanent Link: http://hdl.handle.net/11104/0175981
Number of the records: 1