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Effects of mGluR5 and mGluR1 antagonists on anxiety-like behavior and learning in developing rats

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    0329936 - FGÚ 2010 RIV NL eng J - Journal Article
    Mikulecká, Anna - Mareš, Pavel
    Effects of mGluR5 and mGluR1 antagonists on anxiety-like behavior and learning in developing rats.
    [Vliv antagonistů mGluR5 a mGluR1 na projevy úzkosti a učení u mláďat laboratorního potkana.]
    Behavioural Brain Research. Roč. 204, č. 1 (2009), s. 133-139. ISSN 0166-4328. E-ISSN 1872-7549
    R&D Projects: GA ČR(CZ) GA305/06/1188
    Institutional research plan: CEZ:AV0Z50110509
    Keywords : metabotropic glutamate receptors * anxiety * learning
    Subject RIV: FR - Pharmacology ; Medidal Chemistry
    Impact factor: 3.220, year: 2009

    This study investigated whether the anticonvulsant dose range of MPEP and AIDA affects anxiety-like behavior and learning ability in immature rats. Both MPEP and AIDA exert anxiolytic-like effect. Except for the youngest animals no changes in learning ability in the homing response test were found

    Tato studie byla zaměřena na účinky antikonvulzivních dávek MPEP a AIDA na projevy úzkosti a učení u mláďat laboratorního potkana. Obě látky prokázaly anxiolytický efekt. S výjimkou nejmladších zvířat nebyl prokázán vliv těchto látek na učení
    Permanent Link: http://hdl.handle.net/11104/0175834

     
     
Number of the records: 1  

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