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DNA ligase 1 deficient plants display severe growth defects and delayed repair of both DNA single and double strand breaks

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    0328689 - ÚEB 2010 RIV GB eng J - Journal Article
    Waterworth, W.M. - Kozák, Jaroslav - Provost, C.M. - Bray, C.M. - Angelis, Karel - West, C.E.
    DNA ligase 1 deficient plants display severe growth defects and delayed repair of both DNA single and double strand breaks.
    BMC Plant Biology. Roč. 9, art.no.79 (2009), s. 1-12. ISSN 1471-2229. E-ISSN 1471-2229
    R&D Projects: GA MŠMT 1M0505; GA MŠMT(CZ) LC06004
    Institutional research plan: CEZ:AV0Z50380511
    Keywords : ARABIDOPSIS-THALIANA * T-DNA * COMET ASSAY
    Subject RIV: EB - Genetics ; Molecular Biology
    Impact factor: 3.774, year: 2009

    DNA ligase enzymes catalyse the joining of adjacent polynucleotides and as such play important roles in DNA replication and repair pathways. Eukaryotes possess multiple DNA ligases with distinct roles in DNA metabolism, with clear differences in the functions of DNA ligase orthologues between animals, yeast and plants. DNA ligase 1, present in all eukaryotes, plays critical roles in both DNA repair and replication and is indispensable for cell viability.
    Permanent Link: http://hdl.handle.net/11104/0174941

     
     
Number of the records: 1  

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