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Reduced susceptibility to ischemia-induced arrhythmias in the preconditioned rat heart is independent of PI3-kinase/Akt
- 1.0328562 - FGÚ 2010 RIV CZ eng J - Journal Article
Ravingerová, T. - Matejíková, J. - Pancza, D. - Kolář, František
Reduced susceptibility to ischemia-induced arrhythmias in the preconditioned rat heart is independent of PI3-kinase/Akt.
Physiological Research. Roč. 58, č. 3 (2009), s. 443-447. ISSN 0862-8408. E-ISSN 1802-9973
R&D Projects: GA ČR(CZ) GA305/07/0875; GA MŠMT MEB080837
Grant - others:VEGA(SK) 2/0173/08; APVV(SK) SK-CZ-0049-07
Institutional research plan: CEZ:AV0Z50110509
Keywords : myocardial ischemia * PI3-kinase/Akt * arrhythmias
Subject RIV: FA - Cardiovascular Diseases incl. Cardiotharic Surgery
Impact factor: 1.430, year: 2009
PI3K/Akt inhibition by wortmannin did not affect reduced arrhythmogenesis during ischemia in preconditioned rat hearts indicating that, in contrast to its positive role in the irreversible myocardial injury, PI3K/Akt activity is not required for protection induced by preconditioning against ischemic arrhythmias
Permanent Link: http://hdl.handle.net/11104/0174853
Number of the records: 1