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New hydrophilic HPMA-based polymers for bioreversible shielding of gene delivery vectors
- 1.0328284 - ÚMCH 2010 RIV DE eng J - Journal Article
Laga, Richard - Koňák, Čestmír - Šubr, Vladimír - Ulbrich, Karel
New hydrophilic HPMA-based polymers for bioreversible shielding of gene delivery vectors.
Macromolecular Chemistry and Physics. Roč. 210, 13-14 (2009), s. 1138-1148. ISSN 1022-1352. E-ISSN 1521-3935
R&D Projects: GA AV ČR KAN200200651; GA ČR GA202/09/2078
Institutional research plan: CEZ:AV0Z40500505
Keywords : N-(2-hydroxypropyl)methacrylamide copolymers * polyelectrolyte complexes * latex nanoparticles
Subject RIV: CD - Macromolecular Chemistry
Impact factor: 2.570, year: 2009
New, hydrophilic polymers and copolymers based on HPMA, carrying reactive thiazolidine-2-thione groups either situated at the polymer chain end or randomly distributed along the chains bound to the polymer backbone via spacers containing reductively degradable disulfide linkages, have been developed for an efficient and intracellularly removable coating of gene-delivery vectors.
Permanent Link: http://hdl.handle.net/11104/0174632
Number of the records: 1