Redox transformations in desorption electrospray ionization

0327485 - MBÚ 2010 RIV NL eng J - Journal Article
Benassi, M. - Wu, Ch. - Nefliu, M. - Ifa, D. R. - Volný, Michael - Cooks, R. G.
Redox transformations in desorption electrospray ionization.
International Journal of Mass Spectrometry. Roč. 280, 1-3 (2009), s. 235-240. ISSN 1387-3806. E-ISSN 1873-2798
Institutional research plan: CEZ:AV0Z50200510
Keywords : mass spectrometry * desorption electrospray ionization * oxidation of biomolecules
Subject RIV: CB - Analytical Chemistry, Separation
Impact factor: 2.117, year: 2009

Redox changes occur in some circumstances when organic compounds are analyzed by desorption electrospray ionization mass spectrometry (DESI-MS). However, these processes are limited in scope and the data presented here suggest that there are only limited analogies between the redox behavior in DESI and the well-known solution-phase electrochemical processes in standard electrospray ionization (ESI). Positive and negative ion modes were both investigated and there is a striking asymmetry between the incidence of oxidation and of reduction. Although in negative ion mode DESI experiments, some aromatic compounds were ionized as odd-electron anion radicals, examples of full reduction were not found. By contrast, oxidation in the form of oxygen atomaddition (or multiple oxygen atomadditions)was observed for several different analytes
Permanent Link: http://hdl.handle.net/11104/0174290