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Acid-base-driven matrix-assisted mass spectrometry for targeted metabolomics
- 1.0326519 - ÚOCHB 2010 RIV US eng J - Journal Article
Shroff, R. - Rulíšek, Lubomír - Doubský, J. - Svatoš, Aleš
Acid-base-driven matrix-assisted mass spectrometry for targeted metabolomics.
Proceedings of the National Academy of Sciences of the United States of America. Roč. 106, č. 25 (2009), s. 10092-10096. ISSN 0027-8424. E-ISSN 1091-6490
R&D Projects: GA MŠMT LC512
Institutional research plan: CEZ:AV0Z40550506
Keywords : clinical diagnostic * matrix design * positive/negative ions * MALDI
Subject RIV: CF - Physical ; Theoretical Chemistry
Impact factor: 9.432, year: 2009
An ionization mode of MAILD, a rational protocol for matrix selection based on Bronsted-Lowry acid-base theory and its application to metabolomics, biological screening/profiling/imaging, and clinical diagnostics is presented.
Permanent Link: http://hdl.handle.net/11104/0173601
Number of the records: 1