Pyrrolidine N-alkylphosphonates and related nucleotide analogues: synthesis and stereochemistry

0323918 - ÚOCHB 2009 RIV GB eng J - Journal Article
Rejman, Dominik - Pohl, Radek - Kočalka, Petr - Masojídková, Milena - Rosenberg, Ivan
Pyrrolidine N-alkylphosphonates and related nucleotide analogues: synthesis and stereochemistry.
[Pyrrolidinové alkylfosfonáty a odpovídající analogy nukleotidů: syntéza a stereochemie.]
Tetrahedron. Roč. 65, č. 18 (2009), s. 3673-3681. ISSN 0040-4020. E-ISSN 1464-5416
R&D Projects: GA MŠMT 2B06065; GA MZd NR9138; GA MŠMT(CZ) LC06077; GA MŠMT(CZ) LC06061; GA AV ČR KAN200520801
Institutional research plan: CEZ:AV0Z40550506
Keywords : pyrrolidine * nucleotide * phosphonate
Subject RIV: CC - Organic Chemistry
Impact factor: 3.219, year: 2009

N-Phosphonoalkyl-trans-3,4-dihydroxypyrrolidine derivatives were synthesized and exploited as synthons for the preparation of hydroxypyrrolidine nucleoside phosphonic acids, the 3'-deoxynucleoside 5'- phosphate analogues.

Byly syntetizovány deriváty N-fosfonoalkyl-trans-3,4-dihydroxypyrrolidinu a použity pro syntézu analogů nukleotidů.
Permanent Link: http://hdl.handle.net/11104/0171748