Novel diadenosine polyphosphate analogs with oxymethylene bridges replacing oxygen in the polyphosphate chain. Potential substrates and/or inhibitors of Ap4A hydrolases

0322689 - ÚOCHB 2009 RIV GB eng J - Journal Article
Guranowski, A. - Starzyňska, E. - Pietrowska-Borek, M. - Rejman, Dominik - Blackburn, G. M.
Novel diadenosine polyphosphate analogs with oxymethylene bridges replacing oxygen in the polyphosphate chain. Potential substrates and/or inhibitors of Ap4A hydrolases.
[Nové analogy diadenosin polyfosfátu s oxymethylenovou spojkou místo kyslíkové v polyfosfátovém řetězci.]
FEBS Journal. Roč. 276, č. 6 (2009), s. 1546-1553. ISSN 1742-464X. E-ISSN 1742-4658
Institutional research plan: CEZ:AV0Z40550506
Keywords : diadenosine polyphosphate * oxomethylene * Ap4A hydrolase
Subject RIV: CC - Organic Chemistry
Impact factor: 3.042, year: 2009

Here, we present the results of studies using novel diadenosine polyphosphate analogs, with an oxymethylene group replacing one or two bridging oxygen(s) in the polyphosphate chain. These have been tested as potential substrates and/or inhibitors of the Ap4A hydrolases.

Práce prezentuje výsledky studie analogů diadenosin polyfosfátu s oxymethylenovou spojkou nahrazující jeden nebo dva kyslíkové atomy v polyfosfátovém řetězci. Tyto analogy byly testovány coby substráty či inhibitory Ap4A hydroláz.
Permanent Link: http://hdl.handle.net/11104/0170870