International study of factors affecting human chromosome translocations

0315938 - ÚEM 2009 RIV NL eng J - Journal Article
Sigurdson, A.J. - Ha, M. - Hauptmann, M. - Bhatti, P. - Šrám, Radim - Beskid, Olena - Tawn, E.J. - Whitehouse, C.A. - Lindholm, C. - Nakano, M. - Kodama, Y. - Nakamura, N. - Vorobtsova, I. - Oestreicher, U. - Stephan, G. - Yong, L.C. - Bauchinger, M. - Schmid, E. - Chung, H.W. - Darroudi, F. - Roy, L. - Voisin, P. - Barquinero, J.F. - Livingston, G. - Blakey, D. - Hayata, I. - Zhang, W. - Wang, Ch. - Benett, L.M. - Littlefield, L.G. - Edwards, A.A. - Kleinerman, R.A. - Tucker, J.D.
International study of factors affecting human chromosome translocations.
[International study of factors affecting human chromosome translocations.]
Mutation Research - Genetic Toxicology and Environmental Mutagenesis. Roč. 652, č. 2 (2008), s. 112-121. ISSN 1383-5718. E-ISSN 1879-3592
R&D Projects: GA MŽP SL/5/160/05; GA MŽP SI/340/2/00; GA MŽP SL/740/5/03
Institutional research plan: CEZ:AV0Z50390512
Keywords : Chromosome translocations * FISH * Background frequency
Subject RIV: DN - Health Impact of the Environment Quality
Impact factor: 2.363, year: 2008

Sixteen laboratories in North America, Europe and Asia contributed data on translocation frequencies measured in peripheral blood lymphocytes by fluorescence in situ hybridization (FISH) on 1,400 control individuals. Poisson regression models were used to assess the relation of translocations per 100 cell equivalents (CEs) with age, gender, race (Asian, Black, White) and smoking.

Šestnáct laboratoří ze Severní ameriky, Evropy a Azie poskytlo data o frekvenci translokací, měřených v periferních lymfocytech u 1400 osob metodou fluorescence in situ hybridizace (FISH). Za použití modelů regresní statistické analýzy („poisson regression models“) byly hodnoceny vztahy mezi translokacemi (100 CE) a věkem, pohlavím, rasou (asijská, černá, bílá) a kouřením.
Permanent Link: http://hdl.handle.net/11104/0166004