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Ionic liquids and proteases: A clean alliance for semisynthesis
- 1.0314266 - ÚOCHB 2009 RIV DE eng J - Journal Article
Wehofsky, N. - Wespe, Ch. - Čeřovský, Václav - Pech, A. - Hoess, E. - Rudolph, R. - Bordusa, F.
Ionic liquids and proteases: A clean alliance for semisynthesis.
[Iontové kapaliny a proteazy: Správná kombinace pro semisyntézu.]
Chembiochem. Roč. 9, č. 9 (2008), s. 1493-1499. ISSN 1439-4227. E-ISSN 1439-7633
Grant - others:DFG(DE) SPP1191; DFG(DE) SFB610
Institutional research plan: CEZ:AV0Z40550506
Keywords : chemoenzymatic synthesis * ionic liquids * peptides * proteases * substrate mimetics
Subject RIV: CC - Organic Chemistry
Impact factor: 3.322, year: 2008
Ionic liquids of the type 1,3-dimethyl-imidazolium dimethylphosphate ([MMIM][Me2PO4]) were used as promising additives to promote the protease-catalyzed ligation of cleavage-sensitive peptide and protein fragments without competing peptide bond cleavages.
Iontové kapaliny jako1,3-dimethyl-imidazolium dimethylphosphate ([MMIM][Me2PO4]) byly úspěšně použity jako aditivum pro proteasami katalyzovanou ligaci peptidů nebo fragmentů proteinů bez konkurenčního štěpení jejich peptidových vazeb.
Permanent Link: http://hdl.handle.net/11104/0164834
Number of the records: 1