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Combining combinatorial chemistry and affinity chromatography: highly selective inhibitors of human betaine:homocysteine S-methyltransferase
- 1.0194758 - UOCHB-X 20030063 RIV GB eng J - Journal Article
Collinsová, Michaela - Castro, C. - Garrow, T. A. - Yiotakis, A. - Dive, V. - Jiráček, Jiří
Combining combinatorial chemistry and affinity chromatography: highly selective inhibitors of human betaine:homocysteine S-methyltransferase.
Chemistry & Biology. Roč. 10, - (2003), s. 113-122. ISSN 1074-5521. E-ISSN 1879-1301
R&D Projects: GA AV ČR IAB4055003
Institutional research plan: CEZ:AV0Z4055905
Keywords : BHMT * inhibitor * phosphinic
Subject RIV: CE - Biochemistry
Impact factor: 6.129, year: 2003
A new method to find novel protein targets for ligands of interest is proposed. The principle of this approach is based on affinity chromatography and combinatorial chemistry.
Permanent Link: http://hdl.handle.net/11104/0090429
Number of the records: 1