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The murine endogenous retrovirus MIA14 encodes an active aspartic proteinase that is functionally similar to proteinases from D-type retroviruses
- 1.0194416 - UOCHB-X 20020082 RIV US eng J - Journal Article
Stříšovský, Kvido - Smrž, Daniel - Fehrmann, F. - Kräusslich, H. G. - Konvalinka, Jan
The murine endogenous retrovirus MIA14 encodes an active aspartic proteinase that is functionally similar to proteinases from D-type retroviruses.
Archives of Biochemistry and Biophysics. Roč. 398, č. 2 (2002), s. 261-268. ISSN 0003-9861. E-ISSN 1096-0384
Grant - others:HHMI(GB) 75195-54081
Institutional research plan: CEZ:AV0Z4055905
Keywords : endogenous retrovirus
Subject RIV: CE - Biochemistry
Impact factor: 2.606, year: 2002
We have expressed and purified recombinant MIA14 PR and show that it undergoes N- and C-terminal autoprocessing. MIA14 PR is a catalytically competent enzyme related to the PR of Mason-Pfizer monkey and distinct from HIV-1 PR.
Permanent Link: http://hdl.handle.net/11104/0090091
Number of the records: 1