0194199 - UOCHB-X 20010286 RIV FR eng C - Conference Paper (international conference)
Rall, K. - Čeřovský, Václav - Bordusa, F.
Engineering og trypsin for substrate mimetics-mediated peptide synthesis.
Peptides 2000. Proceedings of the Twenty-Sixth Europen Peptide Symposium. Paris: Éditions EDK, 2001 - (Martinez, J.; Fehrentz, J.), s. 339-340. ISBN 2-84254-048-4.
[Peptides 2000. European Peptide Symposium /26./. Montpellier (FR), 10.09.2000-15.09.2000]
Institutional research plan: CEZ:AV0Z4055905
Keywords : peptide synthesis
Subject RIV: CE - Biochemistry

Site-directed mutagenesis was used to design new trypsin variants which are catalytic active for the synthesis of peptide bonds mediated by substrate mimetics of the 4-guanidinophenyl ester type, but inactive for their cleavage.
Permanent Link: http://hdl.handle.net/11104/0089889