0193829 - UOCHB-X 20000291 RIV NL eng J - Journal Article
Rádl, S. - Hezký, P. - Hafner, W. - Buděšínský, Miloš - Hejnová, L.
Synthesis and Binding Studies of Some Epibatidine Analogues.
Bioorganic and Medicinal Chemistry Letters. Roč. 10, č. 1 (2000), s. 55-58. ISSN 0960-894X. E-ISSN 1464-3405
R&D Projects: GA ČR GA203/96/0112
Institutional research plan: CEZ:AV0Z4055905
Subject RIV: CE - Biochemistry
Impact factor: 1.927, year: 2000

A series of epibatidine analogues and their positional isomers bearing an 8-azabicyclo[3.2.1]octane moiety is described. Some of the compounds, especially those containing 8-azabicyclo[3.2.1]oct-2-ene moiety show high affinity for the nicotinic cholinergic receptor.
Permanent Link: http://hdl.handle.net/11104/0089521