0193802 - UOCHB-X 20000234 RIV CZ eng J - Journal Article
Meszárosová, Kateřina - Holý, Antonín - Masojídková, Milena
Synthesis of acyclic adenine 8,N-anhydronucleosides.
Collection of Czechoslovak Chemical Communications. Roč. 65, č. 7 (2000), s. 1109-1125. ISSN 0010-0765
R&D Projects: GA ČR GV203/96/K001
Institutional research plan: CEZ:AV0Z4055905
Subject RIV: CC - Organic Chemistry
Impact factor: 0.960, year: 2000

9-(4-Hydroxybutyl)-8-bromoadenine was prepared by bromination of 9-(4-hydroxybutyl)adenine. Treatment with thionyl chloride gave 9-(4-chlorobutyl)-8-chloroadenine which was transformed to 6-alkyl-6,7,8,9-tetrahydro-10H-[1,3]diazepino[1,2-e]purine-4-amines or to 6,7,8,9-tetrahydro-10H-[1,3]diazepino[1,2-e]purine-4-amine by reaction with cyclopropylamine, propylamine or ammonia.

Permanent Link: http://hdl.handle.net/11104/0089494