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Tumour-inhibitory effects of dendritic cells administered at the site of HPV 16-induced neoplasms

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    0191464 - UMG-J 20023041 RIV CZ eng J - Journal Article
    Mendoza, Luis - Bubeník, Jan - Šímová, Jana - Korb, Jan - Bieblová, Jana - Vonka, V. - Indrová, Marie - Mikyšková, Romana - Jandlová, Táňa
    Tumour-inhibitory effects of dendritic cells administered at the site of HPV 16-induced neoplasms.
    Folia Biologica. Roč. 48, č. 3 (2002), s. 114-119. ISSN 0015-5500. E-ISSN 0015-5500
    R&D Projects: GA MZd NC7148; GA ČR GA301/00/0114; GA AV ČR IAA7052002; GA AV ČR IAA5052203
    Institutional research plan: CEZ:AV0Z5052915
    Keywords : HPV 16 * dendritic cells * adjuvant therapy
    Subject RIV: EB - Genetics ; Molecular Biology
    Impact factor: 0.615, year: 2002

    It was examined whether administration of APC at the site od HPV 16-associated tumours can inhibit their growth and whether the efficacy of esteblished DC lines is comparable to that of fresh BMDC. The result suggest that local increase in the number of DC can inhibit progression of tumours and that DC may be used for delivery of therapeutic vaccines against HPV 16 neoplasms. The efficacy of established lines and fresh DC was comparable.
    Permanent Link: http://hdl.handle.net/11104/0087216

     
     

Number of the records: 1  

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