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Bone marrow dendritic cell-based anticancer vaccines
- 1.0191425 - UMG-J 20010497 RIV US eng J - Journal Article
Indrová, Marie - Mendoza, Luis - Reiniš, Milan - Vonka, V. - Šmahel, M. - Němečková, Š. - Jandlová, Táňa - Bubeník, Jan
Bone marrow dendritic cell-based anticancer vaccines.
Advances in Experimental Medicine and Biology. Roč. 495, - (2001), s. 355-358. ISSN 0065-2598. E-ISSN 2214-8019
R&D Projects: GA MZd NC5526; GA ČR GA312/98/0826; GA ČR GA312/99/0542; GA ČR GA301/00/0114; GA ČR GA301/01/0985; GA AV ČR IAA7052002
Institutional research plan: CEZ:AV0Z5052915
Keywords : HPV16 * dendritic cells * tumour vaccines
Subject RIV: EB - Genetics ; Molecular Biology
Impact factor: 0.513, year: 2000
Murine carcinoma MK16 was utilized to compare the efficacz of loading dendritic cells with tumour lysates and a synthetic HPV16 E7-derived peptide. It has been found that loading the DC with tumour lysate is more efficient for .I.in vitro priming of syngeneic spleen cells than loading with the immunodominant peptide and that two established DC lines are also able to prime the mitogenic activity of syngeneic spleen cells after loading with antigen.
Permanent Link: http://hdl.handle.net/11104/0087178
Number of the records: 1