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Structural basis of HIV-1 and HIV-2 protease inhibition by a monoclonal antibody
- 1.0191346 - UMG-J 20010417 RIV GB eng J - Journal Article
Řezáčová, Pavlína - Lescar, J. - Brynda, Jiří - Fábry, Milan - Hořejší, Magdalena - Sedláček, Juraj - Bentley, G.
Structural basis of HIV-1 and HIV-2 protease inhibition by a monoclonal antibody.
Structure. Roč. 9, č. 10 (2001), s. 887-895. ISSN 0969-2126. E-ISSN 1878-4186
R&D Projects: GA AV ČR IAA5052502; GA ČR GV203/98/K023
Keywords : single-chain Fv * cross-reactivity * HIV protease
Subject RIV: EB - Genetics ; Molecular Biology
Impact factor: 1.975, year: 2001
Since the demonstration that the protease of the human immunodeficiency virus (HIV Pr) is essential in the viral life cycle, this enzyme has become one of the primary targets for antiviral drug design.
Permanent Link: http://hdl.handle.net/11104/0087099
Number of the records: 1