0181393 - UFCH-W 20020057 RIV DE eng J - Journal Article
Kral, T. - Hof, Martin - Langner, M.
The Effect of Spermine on Plasmid Condensation and Dye Release Observed by Fluorescence Correlation Spectroscopy.
Biological Chemistry. Roč. 383, - (2002), s. 331-335. ISSN 1431-6730. E-ISSN 1437-4315
R&D Projects: GA MŠMT LN00A032
Institutional research plan: CEZ:AV0Z4040901
Keywords : DNA * spermine * fluorescence correlation spectroscopy
Subject RIV: CF - Physical ; Theoretical Chemistry
Impact factor: 2.548, year: 2002

It is demostrated that fluorescence correlation spectroscopy (FCS) can be employed to follow the conformational changes of DNA molecules induced by the addition of a cationic compound (spermine). The data presented show that FCS may become a valuable tool in studiyng supramolecular aggregate formation, especially when association is followed by a change in the hydrodynamic size of the resulting complex.
Permanent Link: http://hdl.handle.net/11104/0077972