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Lesion evolution observed by MRI volumetry in the rat brain after Leksell gamma knife irradiation

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    0173633 - UEM-P 20023053 RIV US eng J - Journal Article
    Jirák, D. - Herynek, V. - Náměstková, Kateřina - Burian, M. - Lisčák, R. - Syková, Eva - Hájek, M.
    Lesion evolution observed by MRI volumetry in the rat brain after Leksell gamma knife irradiation.
    Magnetic Resonance Materials in Physics, Biology and Medicine. Roč. 15, - (2002), s. 185-186. ISSN 0968-5243. E-ISSN 1352-8661.
    [Annual Meeting of the European Society for Magnetic Resonance in Medicine and Biology /19./. Cannes - France, 22.08.2002-25.08.2002]
    R&D Projects: GA MZd NF5161; GA ČR GV309/97/K048; GA MŠMT LN00A065
    Institutional research plan: CEZ:AV0Z5039906
    Keywords : irradiation * MRI volumetry
    Subject RIV: FH - Neurology

    We studied the relation between MR structural changes in the rat brain and the functional impairment observed 14 months after irradiation of the hippocampus by a Leksell Gamma knife (LGK). Our resultss show that if edema is observed, a functional impairment occurs. Our results obtained in an animal model are similar to the description of lesion evolution observed in the human brain after LGK treatment /2/.
    Permanent Link: http://hdl.handle.net/11104/0070662

     
     

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