0173443 - UEM-P 20010038 RIV CZ eng J - Journal Article
Zaid, A. - Hodný, Zdeněk - Li, R. - Nelson, B. D.
Sp1 acts as a repressor of the human adenine nucleotide translocase-2 (ANT2) promoter.
European Journal of Biochemistry. 268:5497-5503, - (2001), s. 1-8. ISSN 0014-2956
Institutional research plan: CEZ:AV0Z5039906
Keywords : mitochondrial promoter * transcription repression
Subject RIV: EB - Genetics ; Molecular Biology
Impact factor: 2.849, year: 2001

We address the mechanism of this unique Sp1-mediated repression using transfected Drosophila SL2 and mammalian cell lines. Data suggest that the D transactivation domain mediates interactions by Sp1 complexes on separate GC elements that results in repression of the activating Sp1 species.
Permanent Link: http://hdl.handle.net/11104/0070476