0173384 - UEM-P 20003108 RIV CZ eng C - Conference Paper (international conference)
Melčák, Ivo - Cermanová, Štěpánka - Raška, Ivan
Spliceosomal Assembly on Precursor mRNA Takes Place in the Nuclear Speckles.
MENDEL 2000. Brno: organizátor symposia, 2000, s. L5-14.
[MENDEL 2000. Brno (CZ), 19.07.2000-23.07.2000]
R&D Projects: GA MŠMT VS96129; GA ČR GA304/00/1481; GA ČR GA302/99/0587
Grant - others:Wellcome Trust grant(XX) 049949/Z/97/Z/JMW/JPS/CG
Institutional research plan: CEZ:AV0Z5039906
Subject RIV: EB - Genetics ; Molecular Biology

Nuclear speckles (speckles), enriched in splicing factors, form a distict nuclear compartment within the interchromatin space. It has been schown to serve vicinal active genes as a reservoir of splicing factors.We show that (pre-)spliceosomal assemblyy on pre-mRNA is associated with the speckles in HeLa cells.
Permanent Link: http://hdl.handle.net/11104/0070417