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The increase of intracellular deoxyribonucleotide pools accelerates the replication in the early S - phase

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    0173376 - UEM-P 20003100 RIV US eng C - Conference Paper (international conference)
    Malínský, Jan - Koberna, Karel - Staněk, David - Mašata, Martin - Raška, Ivan
    The increase of intracellular deoxyribonucleotide pools accelerates the replication in the early S - phase.
    Dynamic organization of nuclear function. New York: Cold Spring Harbor, 2000, s. 129.
    [Dynamic organization of nuclear function. New York (US), 13.09.2000-17.09.2000]
    R&D Projects: GA MŠMT VS96129
    Grant - others:Wellcome Trust grant(XX) 049949/Z/97/Z/JMW/JPS/CG
    Institutional research plan: CEZ:AV0Z5039906
    Subject RIV: EB - Genetics ; Molecular Biology

    We show that the low concetration of deoxyribonucleosidetriphosphates is a rate limiting factor for DNA replication in the early S - phase. The increase of intracellular nucleotide concentrations accelerates the replication process at the beginning off DNA synthesis.
    Permanent Link: http://hdl.handle.net/11104/0070409

     
     

Number of the records: 1  

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